Question:
There are reports which suggest that Cranberry and Resveratrol have anti HSV activity see for e.g:

http://www.invitehealth.com/radio/20...1abstract.aspx

Cranberry Fights Herpes

A new study shows that a polyphenol present in Cranberries fights HSV-2 infection in many ways. HSV-2 is the abreviation for herpes type 2 infection, one of the most common viral infection in humans. HSV-2 is a life long disease once you catch it and during an outbreak sores and ulcers appeare on the genitals. HSV-2 is increasing in incidence worldwide. The polyphenol is a Procyanidin. The study is published in the October 18th 2004 issue of the Journal of the Science of Food and Agriculture.


and


http://www.nutragonllc.com/articles/...ionherpes.html


Antiviral Res. 2004 Jan;61(1):19-26

Effect of topically applied resveratrol on cutaneous herpes simplex virus infections in hairless mice.

Docherty JJ, Smith JS, Fu MM, Stoner T, Booth T.

Department of Microbiology/Immunology, Northeastern Ohio Universities, College of Medicine, PO Box 95, State Route 44, Rootstown, OH 44272, USA. jjd@neoucom.edu

Resveratrol (3,5,4'-trihydroxystilbene) is a natural component of certain foods, such as grapes, that has been shown to have anti-herpes simplex virus (HSV) activity in vitro. To determine if it is active in vivo, the abraded epidermis of SKH1 mice were infected with HSV-1 and topically treated with 12.5 or 25% resveratrol cream or cream only. Initial studies demonstrated that: (1). 25% resveratrol cream topically applied two, three, or five times a day effectively suppressed lesion development whereas 12.5% resveratrol cream effectively suppressed lesion formation when applied five times a day starting 1h after infection; (2). when treatment was begun 1, 6, or 12h after infection, both 12.5 and 25% resveratrol were effective at 1 and 6h after infection, but not if applied 12h after infection. Comparative studies between resveratrol cream, 10% docosanol cream (Abreva) and 5% acyclovir ointment (Zovirax) were also carried out. When treatment was begun 1h after infection and repeated every 3h five times a day for 5 days, 12.5 and 25% resveratrol significantly (P=0.0001) inhibited the development of HSV-1 induced skin lesions. Acyclovir was as effective (P=0.0001) as resveratrol. Animals that were topically treated with docosanol were not protected and developed lesions in a manner indistinguishable from cream only controls. These studies were repeated with an HSV-1 acyclovir-resistant virus. As before, 12.5 and 25% resveratrol cream effectively suppressed lesion formation. The skin of resveratrol-treated animals showed no apparent dermal toxicity such as erythema, scaling, crusting, lichenification, or excoriation. These studies demonstrate that topically applied resveratrol inhibits HSV lesion formation in the skin of mice.


Antiviral Res. 1999 Oct;43(3):145-55
Resveratrol inhibition of herpes simplex virus replication.

Docherty JJ, Fu MM, Stiffler BS, Limperos RJ, Pokabla CM, DeLucia AL.

Department of Microbiology and Immunology, Northeastern Ohio Universities College of Medicine, Rootstown 44272 , USA . jjd@neoucom.edu

Resveratrol, a phytoalexin, was found to inhibit herpes simplex virus types 1 and 2 (HSV-1 and HSV-2) replication in a dose-dependent, reversible manner. The observed reduction in virus yield was not caused by the direct inactivation of HSV by resveratrol nor inhibition of virus attachment to the cell. The chemical did, however, target an early event in the virus replication cycle since it was most effective when added within 1 h of cell infection, less effective if addition was delayed until 6 h post-infection and not effective if added 9 h post-infection. Resveratrol was also found to delay the cell cycle at S-G2-M interphase, inhibit reactivation of virus from latently-infected neurons and reduce the amount of ICP-4, a major immediate early viral regulatory protein, that is produced when compared to controls. These results suggest that a critical early event in the viral replication cycle, that has a compensatory cellular counterpart, is being adversely affected.



Has anyone here tried Cranberry or Resveratrol and what were the results? Please share your thoughts or experiences.

Answer:
Have you tried it?

Angela :D

Answer:
No I have not and therefore wanted to hear other people's experiences.

Answer:
No I have not and therefore wanted to hear other people's experiences. I was hoping to hear what you had thought of these products?

Angela :D